Researchers from Skoltech and other science centers in Russia have developed a reporter system—a tool for screening potential new antibiotics—that enables the selection of drug compounds disrupting RNA synthesis in gram-negative bacteria. Among others, these include multidrug-resistant Pseudomonas aeruginosa, a dangerous pathogen responsible for hospital-acquired infections that has already adapted to existing antibiotics.
France’s biggest film gamble of the year arrives in cinemas as “De Gaulle: Liberté” returns with its second chapter – a €74 million historical epic that’s betting big on international audiences. Film critic Manon Kerjean breaks down whether the ambitious biopic succeeds as a wartime thriller rather than a traditional war movie.