July 7, 2026
Tuberculosis vaccine changes brain’s immune environment and Alzheimer’s biomarkers in older adults

Tuberculosis vaccine changes brain’s immune environment and Alzheimer’s biomarkers in older adults

New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine — which is delivered through the skin to prevent tuberculosis — may remodel the human brain’s immune environment, offering a potential biological explanation for previously observed associations between BCG vaccination and lower Alzheimer’s disease risk.

Read More